IS follows the high school life of Hoshino Haru. Haru was born intersex meaning that he was born with physical characteristics of both sexes and cannot clearly be assigned as a binary gender based on these physical characteristics. Registered as female at birth but later raised as a boy (gender) since he always played with boys his age during the earlier years of school. Haru is forced to attend high school as a girl because of this. ~~ Adapted from the manga "IS – Otoko Demo Onna Demo Nai Sei" (IS 男でも女でもない性) by Chiyo Rokuhana (六花チヨ).